Olanexidine (hydrochloride semihydrate)

Olanexidine (hydrochloride semihydrate)

• CAS Number: 218282-71-4
• UNSPSC Description: Olanexidine hydrochloride semihydrate is an antibacterial agent. Olanexidine hydrochloride semihydrate is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine hydrochloride semihydrate is also an antiseptic. Olanexidine hydrochloride semihydrate can be used in the research of infection and inflammation[1][2][3].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/olanexidine-hydrochloride-semihydrate.html
• Solubility: 10 mM in DMSO
• Smiles: N=C(NC(NCCCCCCCC)=N)NCC1=CC=C(C(Cl)=C1)Cl.O.[1/2].Cl
• Molecular Weight: 417.81
• References & Citations: [1]Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59(8):4551-9.|[2]Nakata H, et al. Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. J Med Microbiol. 2017 May;66(5):678-685.|[3]Imai K, et al. Disinfection efficacy and mechanism of olanexidine gluconate against norovirus. Am J Infect Control. 2022 Jul;50(7):764-771.|[4]Nii T, Yumoto H, Hirota K, Miyake Y. Anti-inflammatory effects of olanexidine gluconate on oral epithelial cells. BMC Oral Health. 2019 Nov 8;19(1):239.
• Shipping Conditions: Room temperature
• Clinical Information: Launched