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Mycro1

CAT: 0804-HY-125636Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-125636Size:1 Each
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Description
Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1].
CAS Number
313987-85-8
UNSPSC
12352005
Target
C-Myc
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mycro1.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C(C=C1)OC)C2=NN3C(C(F)(F)F)=CC(C4=CC=CS4)=NC3=C2
Molecular Formula
C20H15F3N4O2S
Molecular Weight
432.42
References & Citations
[1]Anke Kiessling, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13 (7) :745-51.|[2]Kiessling A, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13 (7) :745-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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