Cyclothialidine

CAT: 0804-HY-125631Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-125631Size:1 Each

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Description

Cyclothialidine (Ro 09-1437) is a potent DNA gyrase inhibitor isolated from Streptomyces filipinensisNR0484[1].

CAS Number

147214-63-9

Product Name Alternative

Ro 09-1437

UNSPSC

12352005

Target

Bacterial; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyclothialidine.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CSCC1=C(O)C=C(O)C(C)=C1C(OC2)=O)C(N[C@@H](C)C(O)=O)=O)[C@H]2NC([C@H]3N(CC[C@H]3O)C([C@@H](N)CO)=O)=O

Molecular Formula

C26H35N5O12S

Molecular Weight

641.65

References & Citations

[1]Angehrn P, et al. New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. J Med Chem. 2004;47 (6) :1487-1513.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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