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Telmesteine

CAT: 0804-HY-125495Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-125495Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
CAS Number
122946-43-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/telmesteine.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H]1N(CSC1)C(OCC)=O
Molecular Formula
C7H11NO4S
Molecular Weight
205.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33 (7) :755-65.|[2]Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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