Poststatin

CAT: 0804-HY-125432Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-125432Size:1 Each

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Description

Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine[1][2].

CAS Number

135219-43-1

UNSPSC

12352209

Target

Prolyl Endopeptidase (PREP)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/poststatin.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](NC([C@@H](CC(C)C)NC(C([C@@H](NC([C@@H](NC([C@@H](N)C(C)C)=O)C(C)C)=O)CC)=O)=O)=O)C(C)C)=O

Molecular Formula

C26H47N5O7

Molecular Weight

541.68

References & Citations

[1]T Aoyagi, et al. Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo) . 1991 Sep;44 (9) :949-55.|[2]M Majima, et al. Poststatin, a novel inhibitor of bradykinin-degrading enzymes in rat urine. Eur J Pharmacol. 1993 Mar 2;232 (2-3) :181-90.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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