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Vincanol

CAT: 0804-HY-124925Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124925Size:1 Each
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Description
Vincanol ((-) -Isoeburnamine) is a blocker of voltage-gated Na+ channels. Vincanol blocks Na+ currents with an IC50 value of 40 μM. Vincanol has neuroprotective effect[1].
CAS Number
19877-89-5
Product Name Alternative
(-) -Isoeburnamine; (-) -epi-Eburnamine
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vincanol.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1N2C3=C(CCN4[C@]3([C@](CC)(C1)CCC4)[H])C5=C2C=CC=C5
Molecular Formula
C19H24N2O
Molecular Weight
296.41
References & Citations
[1]Erdo SA, et al. Vincamine and vincanol are potent blockers of voltage-gated Na+ channels. Eur J Pharmacol. 1996 Oct 24;314 (1-2) :69-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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