Products for Research Use Only
RegisterLogin

Methyl gerfelin

CAT: 0804-HY-124824Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-124824Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat containing protein A (SGTA) . Methyl gerfelin is a potent GLO1 inhibitor related to the flavonoid class[1][2].
CAS Number
700870-56-0
UNSPSC
12352005
Target
Glyoxalase (GLO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/methyl-gerfelin.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)C1=C(C)C=C(OC2=CC(C)=CC(O)=C2O)C=C1O
Molecular Formula
C16H16O6
Molecular Weight
304.29
References & Citations
[1]Kanoh N, et al. Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning. Bioconjug Chem. 2013 Jan 16;24 (1) :44-52. |[2]Perez C, et al. Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. J Med Chem. 2019 Feb 14;62 (3) :1609-1625.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-124723Gerfelin
HY-152650N6-Methyl-2-methyl thioadenosine
HY-W722239Methyl 2- (methyl-d3) butanoate
HY-134716Methyl acetate-PEG1-methyl acetate
HY-W100234-015-Methyl-2′-O-methyl-uridine
HY-152693-01N4-Methyl-2’-O-methyl-cytidine
HY-152611N1-Methyl-5-methyl ara-uridine
HY-145998-012′-O-Methyl-8-methyl guanosine
HY-166007Methyl 11-methyl-12 (E) -octadecenoate
HY-Y0636RMethyl 4-methyl-3-oxopentanoate (Standard)

Alternative Products

CatalogName
MBS5815935Methyl gerfelin
TN9984-01Gerfelin
AR-L05996-01Methyl ?-methyl-4-[ (2-oxocyclopentyl) methyl]benzeneacetate
TRC-M294845-2.5GMethyl Decanoate(Methyl Caprate)
OR1092028Methyl 4-methyl-α-oxobenzeneacetate
OR26323Methyl (methylthio) methyl sulphone
CDA40203-01Methyl acrylamidoglycolate methyl ester
1013001METHYL TRIFLUOROMETHANESULFONATE (METHYL TRIFLATE )
050165-01Chloro Methyl Methyl Ether
455891-01Methyl Decanoate (Methyl Caprate)

Popular Products