Products for Research Use Only
RegisterLogin

Zgwatinib

CAT: 0804-HY-124267Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-124267Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Zgwatinib (SOMG-833) is a potent, selective, and ATP-competitive c-MET inhibitor, with an IC50 of 0.93 nM against c-MET, over 10,000-fold more potent compared with 19 tyrosine kinases (including c-MET family members and highly homologous kinases) . Zgwatinib potently inhibits c-MET-driven cell proliferation. Zgwatinib as a potential candidate agent for c-MET-driven human cancers research[1].
CAS Number
1268264-10-3
Product Name Alternative
SOMG-833
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zgwatinib.html
Solubility
10 mM in DMSO
Smiles
O=[N+]([O-])C1=CC(CNC2=C3C=C(C=NC3=CC(C(F)(F)F)=C2)N4CCN(CC4)C)=CC=C1
Molecular Formula
C22H22F3N5O2
Molecular Weight
445.44
References & Citations
[1]Zhang, H, et al. SOMG-833, a Novel Selective c-MET Inhibitor, Blocks c-MET-Dependent Neoplastic Effects and Exerts Antitumor Activity. Journal of Pharmacology and Experimental Therapeutics, 350 (1), 36–45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
469183-01Zgwatinib

Popular Products