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Nybomycin

CAT: 0804-HY-123635Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-123635Size:500 µg
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Description
Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].
CAS Number
30408-30-1
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nybomycin.html
Purity
99.0
Solubility
Acetic acid : 15 mg/mL (ultrasonic; warming)
Smiles
O=C1N2C3=C(C4=C(C=C3C(C)=C1)C(CO)=CC(N4C)=O)OC2
Molecular Formula
C16H14N2O4
Molecular Weight
298.29
References & Citations
[1]Strelitz F, et, al. NYBOMYCIN, A NEW ANTIBIOTIC WITH ANTIPHAGE AND ANTIBACTERIAL PROPERTIES. Proc Natl Acad Sci U S A. 1955 Sep 15;41 (9) :620-4.|[2]Arai M, et, al. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg Med Chem. 2015 Jul 1;23 (13) :3534-41.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Nybomycin

Nybomycin is a member of quinolines and an aromatic alcohol.

CAS Number30408-30-1
PubChem CID169159
IUPAC Name6-(hydroxymethyl)-3,10-dimethyl-15-oxa-3,13-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(16),2(7),5,8,10-pentaene-4,12-dione
Molecular FormulaC16H14N2O4
Molecular Weight298.29
XLogP-0.5
Topological Polar Surface Area70.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count22
Formal Charge0
Complexity611
SMILES
CC1=CC(=O)N2COC3=C2C1=CC4=C3N(C(=O)C=C4CO)C
InChI
InChI=1S/C16H14N2O4/c1-8-3-13(21)18-7-22-16-14-11(5-10(8)15(16)18)9(6-19)4-12(20)17(14)2/h3-5,19H,6-7H2,1-2H3
InChIKey
HKMUGCUFXWTNSP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Nybomycin
CAS: 30408-30-1
CID: 169159
Formula: C16H14N2O4
MW: 298.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight298.29
XLogP3-0.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass298.09535693
Monoisotopic Mass298.09535693
Topological Polar Surface Area70.1 Ų
Heavy Atom Count22
Formal Charge0
Complexity611
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
461060-01Nybomycin

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