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Metazosin

CAT: 0804-HY-123563Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123563Size:1 Each
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Description
Metazosin (Kenosin) is a potent α1 adrenoceptor blocker. Metazosin is an antihypertensive agent lowering blood pressure[1].
CAS Number
95549-92-1
Product Name Alternative
Kenosin
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/metazosin.html
Solubility
10 mM in DMSO
Smiles
CC(C(N1CCN(CC1)C2=NC(N)=C3C=C(C(OC)=CC3=N2)OC)=O)OC
Molecular Formula
C18H25N5O4
Molecular Weight
375.42
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Lapka R, et al. Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist. Biopharm Drug Dispos. 1989;10 (6) :581-589.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
α adrenergic receptor

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