Kentsin

• UNSPSC Description:

  Kentsin, a contraceptive tetrapeptide, is originally extracted from hamster embryos. Kentsin prevents the maturation of Graafian follicles and consequently inhibits ovulation. Kentsin has opiate properties on gastrointestinal motility[1][3][5].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/kentsin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NCCCC[C@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](N)[C@@H](C)O)=O)=O)CCCNC(N)=N)=O)C(O)=O

• Molecular Weight:

  500.59

• References & Citations:

  [1]Fox DA, et al. Kentsin: tetrapeptide from hamster embryos produces naloxone-sensitive effects without binding to opioid receptors. Peptides. 1987 Jul-Aug;8(4):613-8. |[2]Suk WA, et al. Increased expression of endogenous xenotropic murine retrovirus by treatment with the tetrapeptides, tuftsin and kentsin. J Gen Virol. 1981 Jan;52(Pt 1):189-94. |[3]Bueno L, et al. Central opioid-like influence of a tetrapeptide from hamster embryo (kentsin) on gastrointestinal motility in dogs. Eur J Pharmacol. 1985 Aug 7;114(1):67-70. |[4]Buéno L, et al. A tetrapeptide isolated from hamster embryo with central opiate properties on gastrointestinal motility but not on pain perception. Life Sci. 1986 Jul 14;39(2):141-6. |[5]Wieczorek Z, et al. The immunomodulatory activity of tetra- and tripeptides of tuftsin-kentsin group. Peptides. 1994;15(2):215-21.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  56767-30-7