Products for Research Use Only
RegisterLogin

CRT 0105446

CAT: 0804-HY-123345-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-123345-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM[1].
CAS Number
1661846-05-4
UNSPSC
12352005
Target
LIM Kinase (LIMK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/crt-0105446.html
Solubility
10 mM in DMSO
Smiles
CC(C(NC1=NC=C(S1)C2=C(C=NC=C2)C3=CC=C(C=C3C(F)(F)F)OC)=O)C
Molecular Formula
C20H18F3N3O2S
Molecular Weight
421.44
References & Citations
[1]Mark D Charles, et al. Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties. J Med Chem. 2015 Oct 22;58 (20) :8309-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P5533-01CRT
HY-175493CRT-IN-1
HY-112547CRT5

Alternative Products

CatalogName
E1724-01CRT-0105446

Popular Products