Danshenol B

• Description:

  Danshenol B is a diterpenoid. Danshenol B has strong aldose reductase (AR) inhibitory activity with IC50 value of 0.042μM. Danshenol B can be used for the research of diabetic related complication resulted by metabolic abnormality, such as cataracts, retinopathy, neuropathy, and nephropathy[1].

• UNSPSC:

  12352005

• Target:

  Adenosine Receptor

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/danshenol-b.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@@](CC(C)=O)(O)C2=C(C3=C1[C@@H](C)CO3)C=CC4=C2CCCC4(C)C

• Molecular Formula:

  C22H26O4

• Molecular Weight:

  354.44

• References & Citations:

  [1]Tezuka Y, et al. Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge. Chem Pharm Bull (Tokyo) . 1997 Aug;45 (8) :1306-11.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [189308-09-6]