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Danshenol B

CAT: 0804-HY-122963Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-122963Size:1 Each
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Description
Danshenol B is a diterpenoid. Danshenol B has strong aldose reductase (AR) inhibitory activity with IC50 value of 0.042μM. Danshenol B can be used for the research of diabetic related complication resulted by metabolic abnormality, such as cataracts, retinopathy, neuropathy, and nephropathy[1].
CAS Number
[189308-09-6]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/danshenol-b.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@](CC(C)=O)(O)C2=C(C3=C1[C@@H](C)CO3)C=CC4=C2CCCC4(C)C
Molecular Formula
C22H26O4
Molecular Weight
354.44
References & Citations
[1]Tezuka Y, et al. Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge. Chem Pharm Bull (Tokyo) . 1997 Aug;45 (8) :1306-11.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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