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Zifaxaban

CAT: 0804-HY-122592Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122592Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zifaxaban is an orally active, competitively and selective Factor Xa (FXa) inhibitor with an IC50 of 11.1 nM for human FXa. Zifaxaban shows >10000-fold greater selectivity than other serine proteases. Zifaxaban can be used for the arterial and venous thrombosis research[1].
CAS Number
1378266-98-8
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/zifaxaban.html
Purity
98.37
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(Cl)S1)NC[C@H]2CN(C3=CC=C(N4C=CC=CC4=O)C=C3)C(O2)=O
Molecular Formula
C20H16ClN3O4S
Molecular Weight
429.88
References & Citations
[1]Qiu X, et al. Pre-clinical pharmacodynamic study of a novel oral factor Xa inhibitor zifaxaban. Eur J Pharmacol. 2018 Oct 5;836:50-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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