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Chrysotobibenzyl

CAT: 0804-HY-122552-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122552-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chrysotobibenzyl can be isolated from stem of Dendrobium pulchellum. Chrysotobibenzyl inhibits lung cancer cell (H460 and H292) migration, invasion, filopodia formation via Cav-1, integrins β1, β3, and αν, and EMT suppressions. Chrysotobibenzyl also sensitizes lung cancer cell death mediated by Cisplatin.
CAS Number
108853-09-4
UNSPSC
12352005
Target
Integrin
Type
Natural Products
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/chrysotobibenzyl.html
Solubility
10 mM in DMSO
Smiles
COC1=C(OC)C(OC)=CC(CCC2=CC=C(OC)C(OC)=C2)=C1
Molecular Formula
C19H24O5
Molecular Weight
332.39
References & Citations
[1]Petpiroon N, et al. Chrysotobibenzyl inhibition of lung cancer cell migration through Caveolin-1-dependent mediation of the integrin switch and the sensitization of lung cancer cells to cisplatin-mediated apoptosis. Phytomedicine. 2019 May;58:152888.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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