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8-Deazafolic acid

CAT: 0804-HY-122518Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-122518Size:1 Each
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Description
8-Deazafolic acid is an antimicrobial drug for the folate-dependent bacteria, Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 74691) . 8-Deazafolic acid has activity against lymphoid leukemia L1210 in mice[1].
CAS Number
51989-25-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/8-deazafolic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CC=C(NC(N)=NC3=O)C3=N2)=O)C(O)=O)O
Molecular Formula
C20H20N6O6
Molecular Weight
440.41
References & Citations
[1]Carroll Temple Jr, et al. New synthesis of N-[4-[[ (2-amino-4 (3H) -oxopyrido[3,2-d]pyrimidin-6-yl) methyl]amino]benzoyl]-L-glutamic acid (8-deazafolic acid) and the preparation of some 5,6,7,8-tetrahydro derivatives. J. Med. Chem. 1981, 24, 10, 1254–1258.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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