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CM572

CAT: 0804-HY-122112Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-122112Size:1 Each
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Description
CM572 is a selective irreversible partial sigma-2 receptor agonist. CM572 has antitumor activity. CM572 induces dose-dependent cell death, with an EC50 of 7.6 μM in SK-N-SH neuroblastoma cells. CM572 can be used for the research of kinds of diseases such as neuroblastoma, breast cancer[1].
CAS Number
1121932-91-9
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cm572.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=CC(N=C=S)=CC=C2N1CCCCN3CCN(CC3)C4=CC=C(C=C4)F
Molecular Formula
C22H23FN4O2S
Molecular Weight
426.51
References & Citations
[1]Nicholson H, et al. Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity. J Pharmacol Exp Ther. 2015 Aug;354 (2) :203-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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