ALLO-1

• Description :

  ALLO-1, an autophagy receptor, is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H317-H319-H400

• Target :

  Atg8/LC3; Autophagy

• Type :

  Reference compound

• Related Pathways :

  Autophagy

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/allo-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C(N(C1C)CC2=CC=CC=C2)=O)C3=CC=C(C=C3)Cl

• Molecular Formula :

  C17H15ClN2O2

• Molecular Weight :

  314.77

• Precautions :

  P261-P264-P270-P272-P273-P280-P302+P352-P305+P351+P338-P330-P362+P364-P391-P501

• References & Citations :

  [1]Sato M, et al. The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans. Nat Cell Biol. 2018 Jan;20 (1) :81-91.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [37468-32-9]