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Nemorosone

CAT: 0804-HY-121458Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121458Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nemorosone is the main component of the floral resin of Clusia rosea. Nemorosone has an antiproliferative effect on cancer cells. Nemorosone induces apoptosis in HT-29 and LoVo cells[1][2].
CAS Number
351416-47-2
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nemorosone.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1)[C@@]23C([C@@](C(C(C/C=C(C)/C)=C2O)=O)(C[C@H](C/C=C(C)/C)C3(C)C)C/C=C(C)/C)=O
Molecular Formula
C33H42O4
Molecular Weight
502.68
References & Citations
[1]Frión-Herrera Y, Gabbia D, Scaffidi M, et al. The Cuban Propolis Component Nemorosone Inhibits Proliferation and Metastatic Properties of Human Colorectal Cancer Cells. Int J Mol Sci. 2020;21 (5) :1827. Published 2020 Mar 6.|[2]Wolf RJ, et al. In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts. PLoS One. 2013;8 (9) :e74555. Published 2013 Sep 5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
BA3301-1Nemorosone

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