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Lateritin

CAT: 0804-HY-121407Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121407Size:1 Each
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Description
Lateritin is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), isolated from the mycelial cake of Gibberella lateritium IFO 7188[1]. Lateritin also inhibits the growth of a mini-panel of human cancer cell lines, gram-positive bacteria, and Candida albicans[2].
CAS Number
172721-98-1
UNSPSC
12352005
Target
Acyltransferase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/lateritin.html
Solubility
10 mM in DMSO
Smiles
O=C(O[C@@H]1C(C)C)[C@@H](CC2=CC=CC=C2)N(C)C1=O
Molecular Formula
C15H19NO3
Molecular Weight
261.32
References & Citations
[1]K Hasumi, et al. Lateritin, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Gibberella lateritium IFO 7188. J Antibiot (Tokyo) .1993 Dec;46 (12) :1782-7.|[2]Robin K Pettit, et al. Isolation of human cancer cell growth inhibitory, antimicrobial lateritin from a mixed fungal culture. Planta Med. 2010 Mar;76 (5) :500-1.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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