Muscarine (tosylate)

Muscarine (tosylate)

• CAS Number: 82083-43-0
• UNSPSC Description: Muscarine ((+)-Muscarine) tosylate is an agonist of prototype mAChR. Muscarine tosylate is a toxin that can stimulate the parasympathetic nervous system[1][2].
• Target Antigen: mAChR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/muscarine-tosylate.html
• Solubility: 10 mM in DMSO
• Smiles: C[N+](C)(C)C[C@@H]1C[C@H]([C@@H](O1)C)O.O=S([O-])(C2=CC=C(C=C2)C)=O
• Molecular Weight: 345.45
• References & Citations: [1]Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083. |[2]Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported