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Dipivefrin

CAT: 0804-HY-121398Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121398Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-agent. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2].
CAS Number
52365-63-6
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor; Endogenous Metabolite
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dipivefrin.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C(OC1=CC=C(C=C1OC(C(C)(C)C)=O)C(CNC)O)=O)C
Molecular Formula
C19H29NO5
Molecular Weight
351.44
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Kass MA, et al. Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study. Arch Ophthalmol. 1979 Oct;97 (10) :1865-6.|[2]Alkholief M, et al. Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo. Saudi Pharm J. 2020 Aug;28 (8) :1019-1029.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched