Products for Research Use Only
RegisterLogin

Levobetaxolol

CAT: 0804-HY-121166Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121166Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Levobetaxolol is a potent and high affinity β-adrenergic antagonist with IC50 values of 33.2, 2970, 709 nM for guinea pig atrial β1, tracheal β2 and rat colonic β3 receptors, respectively. Levobetaxolol reduces IOP (intraocular pressure) . Levobetaxolol exhibits a micromolar affinity for L-type Ca21-channels. Levobetaxolol decreases the effects of ischaemia/reperfusion injury in rats. Levobetaxolol has the potential for the research of glaucoma[1][2].
CAS Number
93221-48-8
Product Name Alternative
(S) -Betaxolol
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/levobetaxolol.html
Solubility
10 mM in DMSO
Smiles
O[C@H](COC1=CC=C(C=C1)CCOCC2CC2)CNC(C)C
Molecular Formula
C18H29NO3
Molecular Weight
307.43
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Sharif NA, et al. Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes. J Ocul Pharmacol Ther. 2001 Aug;17 (4) :305-17.|[2]Osborne NN, et al. Effectiveness of levobetaxolol and timolol at blunting retinal ischaemia is related to their calcium and sodium blocking activities: relevance to glaucoma. Brain Res Bull. 2004 Feb 15;62 (6) :525-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

Alternative Products

CatalogName
MBS5772102Levobetaxolol
B1778-50Levobetaxolol HCl
GTR19169805-01Levobetaxolol hydrochloride
RM-B050106-01Betaxolol Impurity 6; Levobetaxolol Hydrochloride

Popular Products