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Serlopitant

CAT: 0804-HY-12114Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12114Size:1 Each
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Description
Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.
CAS Number
860642-69-9
Product Name Alternative
VPD-737; MK-0594
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Serlopitant.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(N2C[C@@]3([H])CC[C@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[C@@H](C5=CC=C(F)C=C5)[C@]3([H])C2)CC1
Molecular Formula
C29H28F7NO2
Molecular Weight
555.53
References & Citations
[1]Yosipovitch G, et al. Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial. J Am Acad Dermatol. 2018 May;78 (5) :882-891.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

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MBS3846010-01Serlopitant
A21582-50Serlopitant 50mg
A21582-25Serlopitant 25mg
A21582-5Serlopitant 5mg
A21582-100Serlopitant 100mg
A21582-10Serlopitant 10mg
A21582-1Serlopitant 1mg

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