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Ceefourin 2

CAT: 0804-HY-121088Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121088Size:1 Each
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Description
Ceefourin 2 is a potent and highly selective inhibitor of MRP4. Ceefourin 2 inhibits the transport of MRP4 substrates but is not selective for other ABC transporters. Ceefourin 2 shows lower cytotoxicity and higher microsomal and acid stability[1].
CAS Number
348148-51-6
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/ceefourin-2.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=NN2C(C(F)(F)F)=CC(C3=CC=C(C=C3)C)=NC2=C1Cl
Molecular Formula
C15H9ClF3N3O2
Molecular Weight
355.70
References & Citations
[1]Cheung L, et al. High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4) . Biochem Pharmacol. 2014 Sep 1;91 (1) :97-108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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