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Daltroban

CAT: 0804-HY-121018Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121018Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist. Daltroban increase intracellular calcium in vascular smooth muscle cells. Daltroban shows protective effect in reperfusion injury[1][2].
CAS Number
79094-20-5
Product Name Alternative
BM-13505; SKF 96148
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/daltroban.html
Purity
98.1
Solubility
DMSO : 22 mg/mL (ultrasonic; warming)
Smiles
O=C(CC1=CC=C(C=C1)CCNS(=O)(C2=CC=C(C=C2)Cl)=O)O
Molecular Formula
C16H16ClNO4S
Molecular Weight
353.82
Precautions
H315, H319, H335
References & Citations
[1]Miki I, et al. Differences in activities of thromboxane A2 receptor antagonists in smooth muscle cells. Eur J Pharmacol. 1992 Oct 1;227 (2) :199-204.|[2]Thiemermann C, et al. The thromboxane receptor antagonist, daltroban, protects the myocardium from ischaemic injury resulting in suppression of leukocytosis. Eur J Pharmacol. 1988 Oct 11;155 (1-2) :57-67.|[3]Bhat AM, et al. Protective effect of the specific thromboxane receptor antagonist, BM-13505, in reperfusion injury following acute myocardial ischemia in cats. Am Heart J. 1989 Apr;117 (4) :799-803.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
TXA2/TP

Alternative Products

CatalogName
T15049-01Daltroban

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