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PF2562

CAT: 0804-HY-120879Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120879Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF2562 (Example 6), a dopamine D1 ligand, ascts as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor with a Ki of 113 nM. PF2562 exhibits activity against human D1 cAMP with an EC50 of 568 nM in HTRF assay[1].
CAS Number
1609258-91-4
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf2562.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(OC2=NC=CC3=C2C=NN3)=CC=C1C4=C(N=CN=C4C)C
Molecular Formula
C19H17N5O
Molecular Weight
331.37
References & Citations
[1]Jennifer Elizabeth Davoren, et al. Heteroaromatic compounds and their use as dopamine d1 ligands. US20140128374A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor

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MBS5769775PF2562