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SEN461

CAT: 0804-HY-120864Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120864Size:1 Each
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Description
SEN461 is a potent and orally active Wnt pathway inhibitor. SEN461 shows effective anti-tumor activity and can be used for GBM research[1].
CAS Number
1287727-28-9
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sen461.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C1=C(C2=O)C=C(C=C1)OC)C)N2C[C@H]3CC[C@@H](CC3)C(N4CCN(CC4)C(COC)=O)=O
Molecular Formula
C25H34N4O6
Molecular Weight
486.56
References & Citations
[1]Nencini, A, et al. Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway. European Journal of Medicinal Chemistry, 95, 526–545.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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