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Enofelast

CAT: 0804-HY-120539Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120539Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC50 of 2.48 μM for inhibition of calcium ionophore-induced LTB4 generation[1].
CAS Number
125722-16-9
Product Name Alternative
BI-L-239
UNSPSC
12352005
Target
Leukotriene Receptor; Lipoxygenase
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/enofelast.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=C(C=C1C)/C=C/C2=CC=C(C=C2)F)C
Molecular Formula
C16H15FO
Molecular Weight
242.29
References & Citations
[1]T C Noonan, et al. Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contraction in vitro. Prostaglandins. 1992 Dec;44 (6) :543-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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