YF479

CAT: 0804-HY-120046Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-120046Size:1 Each

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Description

YF479 is a potent inhibitor of histone deacetylase. YF479 abates cell viability, suppresses colony formation and tumor cell motility. YF479 significantly inhibits breast tumor growth and metastasis. YF479 has the potential for the research of clinical trials for breast cancer[1].

CAS Number

1803281-22-2

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/yf479.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CC1=CC=CC(Br)=C1)C2=CC=C(OC)C=C2OC)CCCCCC(NO)=O

Molecular Formula

C22H27BrN2O5

Molecular Weight

479.36

References & Citations

[1]Zhang T, et al. Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer. Neoplasia. 2014 Aug;16 (8) :665-77.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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