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HS94

CAT: 0804-HY-120040-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-120040-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HS94 is a selective DAPK3 inhibitor. HS94 can be used for research of hypertension[1].
CAS Number
1892594-93-2
UNSPSC
12352005
Target
DAPK
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hs94.html
Purity
98.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C)(SC1=NC(N(C2=CC=CC=C2)N=C3)=C3C(N1)=O)C(N)=O
Molecular Formula
C15H15N5O2S
Molecular Weight
329.38
References & Citations
[1]Carlson DA, et al. Targeting Pim Kinases and DAPK3 to Control Hypertension. Cell Chem Biol. 2018 Oct 18;25 (10) :1195-1207.e32.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

2-Methyl-2-((4-oxo-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)propanamide
CAS Number1892594-93-2
PubChem CID137174459
IUPAC Name2-methyl-2-[(4-oxo-1-phenyl-5H-pyrazolo[5,4-d]pyrimidin-6-yl)sulfanyl]propanamide
Molecular FormulaC15H15N5O2S
Molecular Weight329.4
XLogP1.5
Topological Polar Surface Area128
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity530
SMILES
CC(C)(C(=O)N)SC1=NC2=C(C=NN2C3=CC=CC=C3)C(=O)N1
InChI
InChI=1S/C15H15N5O2S/c1-15(2,13(16)22)23-14-18-11-10(12(21)19-14)8-17-20(11)9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,16,22)(H,18,19,21)
InChIKey
HIGNONZTHOPLMQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-Methyl-2-((4-oxo-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)propanamide
CAS: 1892594-93-2
CID: 137174459
Formula: C15H15N5O2S
MW: 329.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight329.4
XLogP31.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass329.09464591
Monoisotopic Mass329.09464591
Topological Polar Surface Area128 Ų
Heavy Atom Count23
Formal Charge0
Complexity530
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5819455HS94

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