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Befloxatone

CAT: 0804-HY-120017Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120017Size:1 Each
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Description
Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM) . Befloxatone increases the tissue level of monoamine, striatal dopamine and cortical norepinephrine. Befloxatone has antidepressant potential[1].
CAS Number
134564-82-2
Product Name Alternative
MD-370503
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/befloxatone.html
Solubility
10 mM in DMSO
Smiles
O=C1O[C@@H](COC)CN1C2=CC=C(OCC[C@@H](O)C(F)(F)F)C=C2
Molecular Formula
C15H18F3NO5
Molecular Weight
349.30
References & Citations
[1]Curet O, et al. Preclinical profile of befloxatone, a new reversible MAO-A inhibitor. J Affect Disord. 1998 Dec;51 (3) :287-303.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
MAO-A; MAO-B

Alternative Products

CatalogName
MBS5776488Befloxatone

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