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Chloropyramine

CAT: 0804-HY-119995Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119995Size:1 Each
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Description
Chloropyramine is competitive reversible H1 receptor antagonist. Chloropyramine also has anti-tumour activity in breast cancer. Chloropyramine can be used for the research of allergic conditions, such as conjunctivitis and bronchial asthma[1][2].
CAS Number
59-32-5
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Histamine Receptor
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chloropyramine.html
Solubility
10 mM in DMSO
Smiles
CN(CCN(C1=CC=CC=N1)CC2=CC=C(Cl)C=C2)C
Molecular Formula
C16H20ClN3
Molecular Weight
289.80
Precautions
P264-P270-P330-P501
References & Citations
[1]Joshua T Burgess, et al. SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer. Oncotarget. 2016 Nov 8;7 (45) :72807-72818.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor

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