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VU0652835

CAT: 0804-HY-119941Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119941Size:1 Each
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Description
VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM[1].
CAS Number
1848252-81-2
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0652835.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(O[C@@H]2C[C@@H](C)OC2)=CC(C(NC3=NC(C)=CS3)=O)=N1
Molecular Formula
C16H19N3O3S
Molecular Weight
333.41
References & Citations
[1]Felts AS, et al. Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5. Bioorg Med Chem Lett. 2019 Jan 1;29 (1) :47-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR5

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