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Tuberculosis inhibitor 1

CAT: 0804-HY-119938Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119938Size:1 Each
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Description
Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1].
CAS Number
2230810-28-1
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tuberculosis-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
O=C(CC1=C(C)NC2=C1C=C(OC)C=C2)N(CCN(CC3CCOC3)C4)C4C5=NC=C(N5)C6=CC(C=CC=C7)=C7C=C6
Molecular Formula
C34H37N5O3
Molecular Weight
563.69
References & Citations
[1]Ferrigno F, et al. Discovery of 2- (1H-imidazo-2-yl) piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3689-3692.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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