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VU0366248

CAT: 0804-HY-119765Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119765Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0366248 is a mGlu5 negative allosteric modulator[1].
CAS Number
1243310-20-4
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0366248.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(F)=CC(C#N)=C1)NC2=CC=CC(Cl)=C2F
Molecular Formula
C14H7ClF2N2O
Molecular Weight
292.67
References & Citations
[1]Karen J Gregory, et al. Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships. Mol Pharmacol. 2012 Nov;82 (5) :860-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR5

Alternative Products

CatalogName
GTR19198527-01VU0366248

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