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FR198248

CAT: 0804-HY-119728Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119728Size:1 Each
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Description
FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].
CAS Number
197316-54-4
UNSPSC
12352005
Target
Influenza Virus
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fr198248.html
Solubility
10 mM in DMSO
Smiles
OC1OCC2=C1C(O)=C(O)C(O)=C2C
Molecular Formula
C9H10O5
Molecular Weight
198.17
References & Citations
[1]Nishihara Y, et al. FR198248, a new anti-influenza agent isolated from Aspergillus terreus No. 13830 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. The journal of antibiotics, 2001, 54 (2) : 136-143.|[2]Kwon YJ, et al. Isolation and identification of FR198248, a hydroxylated 1,3-dihydroisobenzofuran, from Aspergillus flavipes as an inhibitor of peptide deformylase. Biosci Biotechnol Biochem. 2010;74 (2) :390-3.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported