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Alamifovir

CAT: 0804-HY-119691Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119691Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV) . Alamifovir has high activity against HBV replication and sustained antiviral effect[1][2].
CAS Number
193681-12-8
Product Name Alternative
LY582563; MCC-478
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/alamifovir.html
Purity
95.0
Solubility
DMSO : 5.75 mg/mL (ultrasonic; warming)
Smiles
COC1=CC=C(C=C1)SC2=C3N=CN(C3=NC(N)=N2)CCOCP(OCC(F)(F)F)(OCC(F)(F)F)=O
Molecular Formula
C19H20F6N5O5PS
Molecular Weight
575.42
Precautions
H302, H315, H319
References & Citations
[1]Danny K W Soon, et al. Safety and efficacy of alamifovir in patients with chronic hepatitis B virus infection. J Hepatol. 2004 Nov;41 (5) :852-8.|[2]Suzane Kioko Ono-Nita, et al. Novel nucleoside analogue MCC-478 (LY582563) is effective against wild-type or lamivudine-resistant hepatitis B virus. Antimicrob Agents Chemother. 2002 Aug;46 (8) :2602-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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