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TM5007

CAT: 0804-HY-119160Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119160Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1].
CAS Number
342595-05-5
UNSPSC
12352005
Target
PAI-1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tm5007.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C(C(O)=O)C(C2=CC=CS2)=CS1)CCCCC(NC3=C(C(O)=O)C(C4=CC=CS4)=CS3)=O
Molecular Formula
C24H20N2O6S4
Molecular Weight
560.69
References & Citations
[1]Izuhara Y, et al. Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb Vasc Biol. 2008 Apr;28 (4) :672-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T8962-01TM5007
A22710-100TM5007 100mg
A22710-5TM5007 5mg
A22710-10TM5007 10mg
A22710-500TM5007 500mg
A22710-1TM5007 1mg
A22710-50TM5007 50mg
A22710-25TM5007 25mg

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