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A2315A

CAT: 0804-HY-118593Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118593Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].
CAS Number
58717-24-1
Product Name Alternative
Madumycin II; Antibiotic A 2315A
UNSPSC
12352005
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/a2315a.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H]1C)C2=COC(C[C@@H](C[C@@H](/C=C(\C=C\CNC(/C=C\[C@H]([C@H](OC1=O)C(C)C)C)=O)C)O)O)=N2
Molecular Formula
C26H37N3O7
Molecular Weight
503.59
References & Citations
[1]Osterman IA, et, al. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 2017 Jul 7;45 (12) :7507-7514.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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