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Benzomalvin A

CAT: 0804-HY-118463Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-118463Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].
CAS Number
157047-96-6
Product Name Alternative
(-) -Benzomalvin A
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/benzomalvin-a.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)[C@@H](CC2=CC=CC=C2)C(N3C4=CC=CC=C14)=NC5=C(C=CC=C5)C3=O
Molecular Formula
C24H19N3O2
Molecular Weight
381.43
References & Citations
[1] Sun HH, et al. Benzomalvins, new substance P inhibitors from a Penicillium sp. J Antibiot (Tokyo) . 1994;47 (5) :515-522.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NK1R

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