LY56110

CAT: 0804-HY-118407Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-118407Size:1 Each

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Description

LY56110 is an orally active aromatase inhibitor. LY56110 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 2.5 and 11 μΜ, respectively. LY56110 can be used for neurological disorder study[1][2].

CAS Number

26766-37-0

UNSPSC

12352005

Target

Cytochrome P450; Monoamine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly56110.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C=C1)C(C2=CC=C(C=C2)Cl)C3=CN=CN=C3

Molecular Formula

C17H12Cl2N2

Molecular Weight

315.20

References & Citations

[1]Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8 (4) :595-604.|[2]O'Neill LA, et al. Effect of estrogen inhibitors on conceptus estrogen synthesis and development in the gilt. Domest Anim Endocrinol. 1991;8 (1) :139-153.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

LY56110

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