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Misoprostol acid

CAT: 0804-HY-118189Size: 1 mg (27.14 mM x 100 μL in Methyl Acetate)Dry Ice: NoHazardous: No
CAT#:0804-HY-118189Size:1 mg (27.14 mM x 100 μL in Methyl Acetate)
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Description
Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].
CAS Number
[112137-89-0]
UNSPSC
12352211
Hazard Statement
H301, H315, H319, H335, H361
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/misoprostol-acid.html
Concentration
27.14 mM * 100 μL in Methyl acetate
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Smiles
O[C@H]1[C@@H]([C@H](C(C1)=O)CCCCCCC(O)=O)/C=C/CC(O)(CCCC)C
Molecular Formula
C21H36O5
Molecular Weight
368.51
Precautions
H301, H315, H319, H335, H361
References & Citations
[1]Vijaya Bharathi D, et al. Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 15;879 (26) :2827-33.|[2]Schmidt-Hansen M, et al. Simultaneous compared to interval administration of mifepristone and misoprostol for medical abortion up to 10+0 weeks' gestation: a systematic review with meta-analyses. BMJ Sex Reprod Health. 2020 Feb 20. pii: bmjsrh-2019-200448.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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