GSK951A

CAT: 0804-HY-117741Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-117741Size:1 Each
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Description
GSK951A is a THPP analogue. GSK951A inhibits mycolic acid biosynthesis. GSK951A combines potency in culture with in vivo activity and lack of cytotoxicity[1].
CAS Number
[1403602-33-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gsk951a.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2N(N=C1)[C@@H](C[C@@](C3=CC=C(C=C3)CC)([H])N2)C(F)(F)F)NCC4=CC=C(OCO5)C5=C4
Molecular Formula
C24H23F3N4O3
Molecular Weight
472.46
References & Citations
[1]Cox JA, et al. THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol. 2016;1:15006.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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