a-FABP-IN-1

• UNSPSC Description:

  a-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a Ki below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production[1].

• Target Antigen:

  FABP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/a-fabp-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(OC1=CC(C2=CC=CC=C2C3=NN(C(C4=CC=CS4)=C3)C5=CC=C(C=C5)Cl)=CC=C1)(C(O)=O)C

• Molecular Weight:

  515.02

• References & Citations:

  [1]Liu X, et al. New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg Med Chem Lett. 2011 May 15;21(10):2949-52.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1310361-52-4