Dexchlorpheniramine

• UNSPSC Description:

  Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies[1].

• Target Antigen:

  Histamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dexchlorpheniramine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN(CC[C@@H](C1=CC=C(Cl)C=C1)C2=NC=CC=C2)C

• Molecular Weight:

  274.79

• References & Citations:

  [1]Patkai J, et al. Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain. Pediatr Res. 2001 Aug;50(2):222-30.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  25523-97-1