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Synstab A

CAT: 0804-HY-116915Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116915Size:1 Each
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Description
Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].
CAS Number
257612-36-5
UNSPSC
12352005
Target
Microtubule/Tubulin; Mitosis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/synstab-a.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1)Br)NC(C(Cl)(Cl)Cl)NC2=CC=C(C=C2)S(=O)(N)=O
Molecular Formula
C15H13BrCl3N3O3S
Molecular Weight
501.61
References & Citations
[1]Gerry CJ, et al. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16 (4) :369-378.|[2]Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68 (7) :2292-300.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19192548-01Synstab A

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