Rilmakalim

• Description :

  Rilmakalim (HOE 234) is a potassium channel opener (PCO) that activates ATP-sensitive K+ channels in the heart or other tissues[1].

• Product Name Alternative :

  HOE 234

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/rilmakalim.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(CCC1)[C@H]2[C@@H](C(C)(OC3=C2C=C(C=C3)S(=O)(C4=CC=CC=C4)=O)C)O

• Molecular Formula :

  C21H23NO5S

• Molecular Weight :

  401.48

• References & Citations :

  [1]Kocic, Ivan et al. Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K (+) current in guinea pig ventricular myocytes. Journal of pharmacological sciences vol. 95,2 (2004) : 189-95.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [132014-21-2]