Oosponol

• Description :

  Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi[1][2].

• UNSPSC :

  12352005

• Target :

  Dopamine β-hydroxylase; Fungal

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/oosponol.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1OC=C(C2=C1C(O)=CC=C2)C(CO)=O

• Molecular Formula :

  C11H8O5

• Molecular Weight :

  220.18

• References & Citations :

  [1]Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo) . 1972 Apr;25 (4) :239-42.|[2]Sonnenbichler J, et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246 (1) :45-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [146-04-3]