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SHR168442

CAT: 0804-HY-115879Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115879Size:1 Each
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Description
SHR168442 is a modulator of retinoid-related orphan receptor gamma (RORγ) with an IC50 value of 0.035 μM.
CAS Number
2382961-86-4
UNSPSC
12352005
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/shr168442.html
Solubility
10 mM in DMSO
Smiles
OCC[C@H](C1=CC=C(C=C1)S(CC)(=O)=O)C2=NC3=CC(Cl)=C(N4CCC(F)(CC4)F)C(Cl)=C3N2
Molecular Formula
C23H25Cl2F2N3O3S
Molecular Weight
532.43
References & Citations
[1]Yan Y, et al. Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (rorϒ) and pharmaceutical uses thereof. WO2019213470 A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RORγ

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